Research Interests:
- Discovery of novel drugs for neglected tropical diseases, e.g., malaria
- Identifying therapeutic target for unmet medical needs (diseases)
Research and Publications
- A.W. Karita, D.G. Nyamu, P.N. Karimi, S.C. Gitau. Amphotericin B toxicities among HIV infected adults with Cryptococcal Meningitis in Kiambu District Hospital. Pharmaceutical Journal of Kenya. 2018. Under review
- P Karani, D.G. Nyamu, P.N. Karimi, S.C. Gitau. Assessment of rational drug utilization in patients with Chronic Kidney Disease in Kenyatta National Hospital. African Journal of Pharmacology and Therapeutics. 2018. Under review.
- Xuelian Li, GuoYuan Wang, MuGeQiLi, Haihai Liang, Tianshi Li, XiaoQiang E, YingFeng, Ying Zhang, Xiao Liu, Ming Qian, BoZhi Xu, ZhiHang Shen, , Samuel Chege Gitau, Dan Dan Zhao, Hongli Shan. Aspirin Reduces cardiac Interstitial Fibrosis by inhibiting Erk1/2-serpine2 and P-Akt signaling pathway. Cell Physio Biochem. 2018. DOI:10.1159/000487972
- Xuelian Li, Dandan Zhao, Zhenfeng Guo, Tianshi Li, Muge Qili, Bozhi Xu, Ming Qian, Haihai Liang, Xiaoqiang E, Samuel Chege Gitau, Qiuxia Wu, Lu wang, Chaoqian Xu, Hongli Shan. Overexpression of SerpinE2/protease nexin-1 contribute to pathologiccal cardiac fibrosis via increasing collagen deposition. http://www.nature.com. 2016. ISSN 2045-2322
- Samuel chege Gitau, Xuelian Li, Dandan Zhao, Zhenfeng Guo, Haihai Liang, Ming Qian，Lifang Lv，Tianshi Li，Bozhi Xu，Zhiguo Wang，Yong Zhang，Chaoqian Xu，Yanjie Lu，Zhiming Du, Hongli Shan, Baofeng Yang. Acetyl salicylic acid attenuates cardiac hypertrophy through Wnt signaling. Frontiers of Medicine. 2015. DOI: 10.1007/s11684-015-0421-z
- Wang L, Li L, Guo R, Li X, Lu Y, Guan X, Gitau SC, Wang L, Xu C, Yang B, Shan H. miR-101 promotes breast cancer cell apoptosis by targeting Janus kinase 2. Cell Physiol Biochem. 2014; 34(2):413-422. (SCI 3.55)
- Zhou X, Zhang Q, Zhao T, Bai X, Yuan W, Wu Y, Liu D, Li S, Ju J, Chege Gitau S, Chu W, Xu C, Lu Y. Cisapride protects against cardiac hypertrophy via inhibiting the up-regulation of calcineurin and NFATc-3. Eur J Pharmacol. 2014; 735:202-210. (SCI 2.684)
- Liang H, Xu C, Pan Z, Zhang Y, Xu Z, Chen Y, Li T, Li X, Liu Y, Huangfu L, Lu Y, Zhang Z, Yang B, Gitau S, Lu Y,Shan H, Du Z. The antifibrotic effects and mechanisms of microRNA-26a action in idiopathic pulmonary fibrosis. Mol Ther. 2014; 22(6):1122-1133. (SCI 6.425)
|
