Name: Dr. Wycliffe Arika Makori.
Qualification: PhD
Position :Lecturer
Department: Biochemistry, Microbiology and Biotechnology
Address: P.O. Box 43844, 00100,Nairobi, Kenya
Email: This email address is being protected from spambots. You need JavaScript enabled to view it. or This email address is being protected from spambots. You need JavaScript enabled to view it.

Area of Specialization: Medical Biochemistry and Medical Oncology

Research Interests: Diabetes Mellitus, Obesity, Neurodegenerative disorders (Cognitive impairments and spontaneously emitted behaviors viz. locomotor activity, anxiety and exploration) and Medical Oncology (Cancer).

ORCID: https://orcid.org/0000-0002-6928-4158

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PUBLICATIONS

2023

A Pre-print:

  1. Junnan Liu, Xue Wang, Anca Azoitei, Tim Eiseler, Sabine Meessen, Wencheng Jiang, Xi Zheng, Arika W. Makori, Christian Bolenz …. & Cagatay Günes. (2023). "Novel ploidy­control genes ORP3 and GJB3 link aneuploidy to tumor cell invasion through microtubule and actin dynamics"

2020

  1. Xu, P., Richter, J., Blatz, A., Gärtner, F., Alberts, R., Azoitei, A., Makori, W.A., ... & Günes, C. (2020). Downregulation of ORP3 Correlates with Reduced Survival of Colon Cancer Patients with Advanced Nodal Metastasis and of Female Patients with Grade 3 Colon Cancer. International Journal of Molecular Sciences, 21: 5894.
  2. Ruth, K.M., Warutere, P.N., Nyamari, J., & Arika, W. (2020). Levels of Ionizing Radiations in Selected Quarries in Nyamira County, Kenya. Heliyon, 6: e04363.

2019

  1. Arika, W.M., Kibiti, C.M., Njagi, J.M., & Ngugi, M.P. (2019). Anti˗Obesity Effects of Dichloromethane Leaf Extract of Gnidia glauca in High Fat Diet-Induced Obese Rats. Heliyon, 5: 1˗ doi.org/10.1016/j.heliyon. 2019.e02800.
  2. Arika, W.M, Kibiti, C.M., Njagi, J.M., & Ngugi, M.P. (2019). In Vitro Antioxidant Properties of Dichloromethanolic Leaf Extract of Gnidia glauca (Fresen) as a Promising Antiobesity Drug. Journal of Evidence-Based Integrative Medicine, 24:1˗ doi.org/10.1177/2515690X19883258.
  3. Arika, W.M., Kibiti, C.M., Njagi, J.M., & Ngugi, M.P. (2019). Modulation of Cognition: The Role of Gnidia glauca on Spatial Learning and Memory Retention in High-Fat Diet-Induced Obese Rats. Neural plasticity, 2019: 1˗ doi.org/10.1155/2019/2867058.
  4. Arika, W.M., Kibiti, C.M., Njagi, J.M., & Ngugi, M.P. (2019). Effects of DCM Leaf Extract of Gnidia glauca (Fresen) on Locomotor Activity, Anxiety, and Exploration˗Like Behaviors in High˗Fat Diet-Induced Obese Rats. Behavioural Neurology, 2019: 1˗ doi.org/10.1155/2019/7359235.

2018

  1. Njogu, S.M., Arika, W.M., Machocho, A.K., Ngeranwa, J.J., & Njagi, E.N. (2018). In Vivo Hypoglycemic Effect of Kigelia africana (Lam): Studies with Alloxan-Induced Diabetic Mice. Journal of Evidence-Based Integrative Medicine, 23: 1˗ doi.org/10.1177/2515690.

2017

  1. Ouko, R.O., Koech, S.C., Arika, W.M., Njagi, S.M., & Oduor, R.O. (2017). Bioefficacy of Organic Extracts of Ocimum basilicum against Sitophilus zeamais. Entomology, Ornithology and Herpetology, 6: 1˗ doi: 10.4172/2161˗0983.1000190.
  2. Stephen, N.M., Wycliffe, A.M., Alex, M.K., Joseph, N.J., & Eliud, N.N. (2017). In vivo antidiabetic activity of aqueous and ethyl acetate leaf extract of Senna singuena (Delile) in alloxan induced diabetic mice. The Journal of Phytopharmacology, 6: 84˗ X 18768727.

2016

  1. Arika, W.M., Nyamai, D.W., Musila, M.N., Ngugi, M.P., Njagi, E.N.M (2016). Hematological Markers of In Vivo Journal of Hematology and Thromboembolic Diseases, 4: 236. doi:10.4172/2329˗8790.1000236.
  2. Arika, W.M., Nyamai., D.W., Osano, K.O., Ngugi, M.P., Njagi, E.N.M (2016). Biochemical Markers of In Vivo Journal of Clinical Toxicology, 6: 297.doi:10.4172/2161˗0495.1000297.
  3. Arika, W.M., Nyamai, D.W., Agyirifo, D.S., Ngug, M.P., Njagi, E.N.M. (2016). In Vivo Antidiabetic Effect of Aqueous Leaf Extract of Azardirachta indica, A. Juss in Alloxan Induced Diabetic Mice. Journal of Diabetic Complications and Medicine, 1: 106. doi:10.4172/jdcm.1000.106.
  4. Arika, W.M., Ogola, P.E., Nyamai, D.W., Mawia, A.M., Wambua, F.K., et al. (2016). Mineral Elements Content of Selected Kenyan Antidiabetic Medicinal Plants. Advanced Techniques in Biology and Medicine, 4: 160. doi: 10.4172/2379˗1000160.
  5. Arika, W.M., Rachuonyo, H.O., Muchori, A.N., Lagat, R.C., Mawia, A.M., et al. (2016) Hypoglycemic Effect of Ocimum Lamiifolium in Alloxan Induced Diabetic Mice. Med Aromat Plants 5: 228. doi:10.4172/2167-0412.1000228
  6. Nyamai, D.W., Arika, W.M., Ogola, P.E., Njagi, E.N.M., Ngugi, M.P. (2016). Medicinally Important Phytochemicals: An Untapped Research Avenue. Journal of Pharmacognosy and Phytochemistry, 4: 35˗ e˗ISSN:2321˗6182.
  7. Ogola, P.E., Arika, W.M., Nyamai, D.W., Osano, K.O., & Rachuonyo, H.O. (2016). Determination of Background Ionizing Radiations in Selected Buildings in Nairobi County, Kenya. Journal of Nuclear Medicine and Radiation Therapy, 7: 2. doi:10.4172/2155˗9619.1000289.
  1. Nyamai, D.W., Arika, W.M., Rachuonyo, H.O., Wambani, J.R., & Ngugi, M.P. (2016). Herbal Management of Benign Prostatic Hyperplasia. Journal of Cancer Science and Therapy, 8: 130˗ doi:10.4172/1948˗5956.1000404.
  2. Muruthi, C.W., Lwande, O.W., Makumi, J.N., Runo, S., Otiende, M., & Makori, W.A. (2016). Phenotypic and Genotypic Identification of Ticks Sampled from Wildlife Species in Selected Conservation Sites of Kenya. Journal of Veterinary Science and Technology, 7: 2. doi:10.4172/2157-7579.1000293.
  3. Njogu, S.M., Arika, W.M., Nyamai, D.W., Ngugi, M.P., Machocho, A.K., Ngeranwa, J.J.N., & Njagi, E.N.M. (2016). Hypoglycemic Effect of Aqueous and Ethyl Acetate Leaf Extract of Maytenus putterkloides in Alloxan Induced Diabetic Mice. Journal of Diabetes and Metabolism, 7: 2. doi:10.4172/2155-6156.1000685.
  4. Wambani, J.R., Ogola, P.E., Arika, W. M., Rachuonyo, H.O., & Burugu, M.W. (2016). Global Situation and Trends of HIV, Influenza and Marburg Viruses: An Epidemiological Perspective. Emerging Infectious Diseases journal, 1: 2. doi:10.4172/jeid.1000105.
  5. Wambani, J.R., Kiboi, N.G., Makori, W.M., Ogola, P.E., & Rachuonyo, H. O. (2016). Immunological Profiles in HIV Positive Patients with or Without Opportunistic Infections and The Influence of Highly Active Antiretroviral Therapy: A Systematic Review and Update. Journal of Clinical and Cellular Immunology, 7: 2. doi:10.4172/2155˗1000429.
  6. Osano, K.O., Nyamai, D.W., Ogola, P.E., Ouko, R.O., & Arika, W.M. (2016). Evaluation of In Vivo Toxicity of Dichloromethane: Methanolic Leaf Extracts of Prosopis juliflora in Female Wistar Albino Rats. Journal of Drug Metabolism and Toxicology, 7: 1˗ doi:10.4172/2157-7609.1000200.
  7. Njagi, S.M., Lagat, R.C., Mawia, A. M., Arika, W.M., Wambua, F.K., Ouko, R.O., ... & Mwitari, P.G. (2016). In Vitro Antiproliferative Activity of Aqueous Root Bark Extract of Cassia abbreviata (holmes) Brenan. Journal of Cancer Science and Clinical Therapeutics, 8: 114˗ doi:10.4172/1948-5956.1000402.
  8. Rachuonyo, H., Ogola, P., Arika, W., Wambani, J., & Gatheri, G. (2016). Combined Effect of Crude Leaf Extracts of Selected Medicinal Plants Against Selected Enteric Bacterial Pathogens and Candida albicans. Journal of Antimicrobial Agents, 2: 110. doi:10.4172/2472˗1000110.
  9. Wambani, R.J., Ogola, P.E., Arika, W.M., Rachuonyo, H.O., & Burugu, M.W. (2016). Ebola Virus Disease: A Biological and Epidemiological Perspective of a Virulent Virus. Journal of Infectious Diseases and Diagnosis, 1: 103. doi: 2. 4172/jidd.1000103.
  10. Rachuonyo, H.O., Ogola, P.E., Arika, W.M., Kiboi, N.G., & Wambani, J.R. (2016). Antimicrobial Potency of Methanolic Leaf Extracts from Selected Medicinal Plants against Staphylococcus aureus. Journal of Medical Microbiology and Diagnosis, 5: 219. doi:10.4172/2161˗1000219.

 

2015

  1. Arika, W.M., Abdirahman, Y.A., Mawia, M.A. et al. (2015). In Vivo Antidiabetic Activity of the Aqueous Leaf Extract of Croton macrostachyus in Alloxan Induced Diabetic Mice. Pharmaceutica Analytica Acta, 6: 447. doi: 10.4172/21532435.1000447.
  2. Arika, W.M., Abdirahman, Y.A., Ogola, P.E., Kiboi, N.G., Njagi, S.M., et al. (2015). Hypoglycemic Effect of Lippia javanica in Alloxan Induced Diabetic Mice. Journal of Diabetes and Metabolism, 6: 624. doi:10.4172/2155˗1000624.
  3. Arika, W.M., Ogola, P.E., Abdirahman, Y.A., Mawia, A.M., Wambua, F.K., Nyamai, D.W., et al. (2015). In Vivo Safety of Aqueous Leaf Extract of Lippia javanica in Mice Models. Journal of Physiology and Biochemistry, 5: 191. doi: 10.4172/2168˗1000191.
  4. Kioko, W.F., Mawia, M.A., Piero, N.M., Muriira, K.G., Wavinya, N.D., Chemutai, L. R., Arika, W.M... & Mwenda, N. S. (2015). Phenotypic Characterization on Selected Kenyan And Tanzanian Rice (Oryza sativa) Populations Based on Grain Morphological Traits. Journal of Rice Research, 3: 4. doi:10.4172/2375˗4338.1000155.
  5. Nyamai, D. W., Mawia, A. M., Wambua, F. K., Njoroge, A., Matheri, F., Lagat, R., Arika, W.M., & King’ori, E. (2015). Phytochemical Profile of Prunus africana Stem Bark from Kenya. Journal of Pharmacognosy and Natural Products, 1:1˗ doi:10.4172/2472˗0992.1000110.
  6. Wambani, J.R., Ogola, P.E., Arika, W.M., Rachuonyo, H.O., Kemboi, N.G., Lihana, R., & Burugu, M. W. (2015). Anti˗Retroviral Drug Hepatotoxicity and Risk Factors in HIV Patients with or Without Hepatitis B and C: a review. Journal of Infectious Diseases and Therapy, 3: 1˗ doi:10.4172/2332˗0877.1000258
  7. Mawia Musyoki, A., Wambua Kioko, F., Daniel, A., Nyamai Wavinya, D., Arika, W., & Felix, M. (2015). Phenotypic Diversity Studies on Selected Kenyan and Tanzanian Rice (Oryza sativa L) Genotypes Based on Grain and Kernel Traits. Journal of Rice Research, 3: 2˗ doi:10.4172/2375˗4338.1000150.
  8. Abdirahman, Y.A., Juma, K.K., Makori, W.A., Agyirifo, D.S., Ngugi, M.P., Gathumbi, P.K., ... & Njagi, E.N.M. (2015). Blood Glucose Lowering Effect and Safety of The Aqueous Leaf Extracts of Zanha africana. Pharmaceutica Analytica Acta, 6: 1˗ doi:10.4172/21532435. 1000422.
  9. Wambani, R.J., Ogola, P.E., Makori, A.W., Nyamai, D.W., Lihana, R., et al. (2015) Hepatitis B and C Co-Infections among HIV˗1 Infected Patients Attending the Academic Model Providing Access to Healthcare Clinic, Kenya, 2014. Journal of Infectious Diseases and Diagnosis, 1: 102. doi:10.4172/jidd.1000102.
  10. Nyamai DW, Mawia AM, Wambua FK, Abdirahman YA, Osano K, Lagat, R., Mumbi, B., Arika, W., Juma, K.K., et al. (2015) Growth Performance of Domesticated Prunus africana Population in Muguga, Kiambu County, Kenya. Biochemistry and Physiology, 4: 185. doi: 10.4172/2168˗1000185.